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NEW • AUG 2026

167M PARAMS +0.15 AUC vs ESM2 PROTEINGYM SOTA

PRESS RELEASE August 2026 • bioRxiv Preprint

AINN-P1: Small Model, Big Intelligence

A 167M-parameter sequence-first protein foundation model that leads ProteinGym on stability and generalizes to unseen antibody programs — outperforming the 650M ESM2 by 0.15 AUC on new programs with 3.9× fewer parameters, and beating a 100B-parameter model on stability by 39%.

Dr. Lurong Pan

Founder & CEO, Ainnocence

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SENTINUSAI® • JUL 2026

91.4% SUCCESS 28 PROGRAMS TO LICENSE

PRESS RELEASE July 10, 2026

Ainnocence Reports 91.4% Program Success Rate Across 58 Antibody Affinity Maturation Campaigns

Structure-free AI platform delivers picomolar leads while cutting wet-lab validation to 20–50 samples per round. Ainnocence opens a 28-program biologics pipeline — antibody, bispecific and ADC assets across oncology, immunology and metabolic indications — to licensing and partnering.

Interviews & Webinars

Wall Street Journal • Dec 2022

Dr. Lurong Pan’s Wall Street Journal Interview

How AI that powers chatbots and search queries could discover new drugs.

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YouTube • Webinar

Dr. Lurong Pan on Protein LLM and Generative AI in Protein Engineering

Deep dive on protein language models and generative AI for antibody / protein design.

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Info-Tech Research • Thought Leader

Info-Tech Thought Leader Interview with Dr. Lurong Pan

How AI is used in modern drug design — enterprise perspective.

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YouTube • Q&A

Dr. Lurong Pan Answers FAQs about AI

Frequently asked questions about AI in biotech, answered.

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Sino Biological • Podcast

BioBuzz with Sino: ChatGPT in Biotech

Podcast episode on generative AI transforming biotech workflows.

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YouTube • Case Study

AI-Designed Mutation-Resistant Broad Neutralization Antibodies Against Multiple SARS-CoV-2 Strains

Case study on rapid pandemic-response antibody design.

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Dataiku • AI & US Series

Dataiku AI&US Episode 1: Making The Breakthrough

Featured in Dataiku's flagship AI storytelling series.

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2026 Press Releases

BioSpace • Sep 2026

Ainnocence Shows AINN-P1 Protein Foundation Model Improves Antibody–Antigen Affinity Ranking by 28% — From Sequence Alone

167M-parameter model beats 650M ESM2 by 0.15 AUC on unseen antibody programs.

Latest News

AINN-P1: Small Model, Big Intelligence

Ainnocence Reports 91.4% Program Success Rate Across 58 Antibody Affinity Maturation Campaigns

Dr. Lurong Pan’s Wall Street Journal Interview

Dr. Lurong Pan on Protein LLM and Generative AI in Protein Engineering

Info-Tech Thought Leader Interview with Dr. Lurong Pan

Dr. Lurong Pan Answers FAQs about AI

BioBuzz with Sino: ChatGPT in Biotech

AI-Designed Mutation-Resistant Broad Neutralization Antibodies Against Multiple SARS-CoV-2 Strains

Dataiku AI&US Episode 1: Making The Breakthrough

Ainnocence Shows AINN-P1 Protein Foundation Model Improves Antibody–Antigen Affinity Ranking by 28% — From Sequence Alone

Ainnocence’s AINN-P1 Demonstrates Efficient Protein Prediction and Antibody Engineering

Ainnocence Shows Its Protein Foundation Model Improves Antibody–Antigen Affinity Ranking by 28%

Ainnocence Reports 91.4% Success Across 58 Antibody Affinity Maturation Campaigns, Opens 28-Program Biologics Pipeline to Licensing

Ainnocence Reports 91.4% Success Across 58 Antibody Affinity Maturation Campaigns

Ainnocence Brings Its Protein, Antibody, and Peptide AI Models to Production as Secure, On-Demand APIs

Ainnocence Brings Its Protein, Antibody and Peptide AI Models to Production as Secure, On-Demand APIs

Ainnocence Proposes a Seven-Rule Governance Framework and Value Scorecard for AI-Driven Drug Discovery

Ainnocence PeptideAI Platform Screens 3.2M Peptides with 90%+ Accuracy

Ainnocence’s CarbonAI®: A Proprietary AI Engine for De Novo Small-Molecule and PROTAC Design

SentinusAI® Goes Live: Ainnocence’s AI Platform Turns Sequence Data Into Discovery Decisions in Days

Destructed Drug Discovery: Sequence-Based AI Achieves Whole-Genome Screening in Hours

How Sequence-Based AI Achieves Whole-Genome Screening for Billions of Candidates in Hours

Ainnocence Calls for Global Collaboration to Deploy AI-Driven Antibody and Vaccine Discovery Against the World’s Deadliest Infectious Diseases

Ainnocence Calls for Collaboration to Deploy AI-Driven Antibody Discovery Against the World’s Deadliest Infectious Diseases

NatmolAI™: Computational Expansion and Optimization of Natural-Product Chemical Space

Beauty Engineered: Ainnocence Launches CosmeticAI™ to Accelerate AI-Driven Innovation in Skincare and Beauty Products

AI Meets the Formula: Predictive Intelligence Redefines Chemical Design and Manufacturing

From Code to Cure: Accelerating Oligonucleotide Design with AI

RNA Reimagined: Harnessing AI to Unlock mRNA and siRNA Therapies

Ainnocence Announces AI Platform for Material Performance Prediction and Process Optimization

Ainnocence Expands the Druggable Universe: Targeting Therapeutics Without Structural Data

Antibody Design at Lightning Speed: AI-Driven Precision for Complex Targets

Beyond the Library: 10¹⁰ Virtual Compounds and Antibody Variants Screened Overnight

Redefining Chemistry: How AI Shrinks Small-Molecule Discovery from Years to Weeks

Ainnocence Achieves New Milestone with Protein Foundation Models

SentinusAI® Demonstrates Consistent Superior Performance in Protein Design, Outperforming Competitors

Ainnocence Launches BioSynthAI Platform for AI-Driven Synthetic Biology Product Discovery

Ainnocence Unveils Core Challenges Undermining AI-Driven Small-Molecule Drug Discovery

Obatala Sciences and Ainnocence Announce Partnership to Transform Drug Discovery Through AI and Human Biological Models

Ainnocence Achieves 10,000× Reduction in Computational Cost for Protein Design Without 3D Modeling

Ainnocence Demonstrates Breakthrough AI Technology for Rapid Pandemic Response

Advanced Generative AI Platform Achieves Computational Efficiency Breakthrough in Therapeutic Protein Engineering

AI Breakthrough Ushers in New Era of Personalized Medicine

Turbocharging Drug Discovery: AI-Powered R&D Is Transforming Pharma

Revolutionizing Molecular Design Beyond 3D Modeling: Protein Language Models Unlock New Frontiers

Ainnocence Unveils Advanced AAV Design Services to Revolutionize Gene Therapy

Ainnocence Launches CellulaAI™: A Pioneering AI Engine to Revolutionize CAR-T Therapy

Ainnocence Unveils SentinusAI®: Revolutionizing Antibody Design, Conquering Undruggable Targets, Rescuing Failed Trials

Ainnocence Embraces Green AI and Animal-Free Drug Screening

Ainnocence Unveils Innovative AI-Enabled Platform for Antibody Affinity Maturation and GPCR Antibody Design

AI-Powered Fast and Cost-Effective Antibody De Novo Design and Affinity Maturation Service Unveiled

AI-Powered Fast and Cost-Effective Antibody De Novo Design and Affinity Maturation Service Unveiled

Ainnocence Launches Self-Evolving, Multi-Objective AI Drug Discovery Platform

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Ainnocence and Phase Advance Enter Industry-First AI Collaboration to Reduce Drug Development Timeline and Clinical Trial Risk

Ainnocence Patents

Ainnocence Publications

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